Clearly Hormonal

with Dr. Komal Patil-Sisodia

Hormonal health, without the confusion.

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37: Midlife & Menopause: The 2025 Report
Komal Patil-Sisodia Komal Patil-Sisodia

37: Midlife & Menopause: The 2025 Report

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia highlights the transformative year of 2025 in women's health, focusing on menopause care. Key topics include the FDA's rewording of black box warnings on hormone therapy, breakthrough non-hormonal treatments, and the American Heart Association's new cardiovascular guidelines.

The podcast also covers advances in weight management, bone health, and preventive screenings, along with the elevation of lifestyle medicine and the growing field of fem tech.

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36: Presence Over Perfection: A Midlife Anti-Burnout Strategy
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36: Presence Over Perfection: A Midlife Anti-Burnout Strategy

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia shares her personal experiences with burnout and emphasizes the importance of being present and pausing. She discusses how striving for perfection can lead to deep mental and physical exhaustion, especially for midlife women.

Dr. Patil-Sisodia dives into the concept of the burnout-inactivity trap, where chronic burnout reduces physical activity, further exacerbating physical decline. She outlines effective strategies for breaking this cycle, including consistent moderate physical activity and prioritizing quality sleep. The episode concludes with actionable tips on integrating more movement, connection, and genuine rest into daily life to combat burnout.

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35: Understanding Progestogens in Menopause Hormone Therapy
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35: Understanding Progestogens in Menopause Hormone Therapy

Menopause hormone therapy (MHT) can feel like a maze—especially when you start hearing terms like progesterone, progestin, and progestogen used interchangeably. If you’ve ever thought, “Wait… are these all the same thing?” you’re not alone.

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia breaks down one of the most important—and most confusing—parts of menopause care: progestogens. By the end, you’ll know what these hormones do, why they’re essential for many women, and how different options fit different bodies and risk profiles.

Let’s reset the confusion and recharge your hormone literacy.

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34: Understanding Estrogen: Facts vs. Myths
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34: Understanding Estrogen: Facts vs. Myths

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia, a triple board certified endocrinologist and women's health expert, explores the complexities of estrogen therapy. She breaks down bioidentical and synthetic estrogen, compares their safety and effectiveness, and provides evidence-based insights into cardiovascular and cancer risks.

This informative session aims to empower women with the knowledge to make informed decisions about hormone therapy. Dr. Patil-Sisodia emphasizes the importance of understanding individual risk factors and the critical distinctions between FDA-approved and compounded hormone products.

Tune in for a deep dive into estrogen therapy, and learn practical questions to bring to your next healthcare appointment.

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33: Midlife Skincare with Dr. Sarah Stierman
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33: Midlife Skincare with Dr. Sarah Stierman

If your skin suddenly feels drier, more sensitive, or just “not like it used to be,” you’re not imagining it. Perimenopause and menopause are a full-body hormonal shift—and your skin is absolutely part of that story.

In this episode of Reset Recharge, I’m joined by Dr. Sarah Stierman, a board-certified dermatologist and dermatopathologist, to break down what actually works for midlife skin, what’s overhyped, and where hormones and skincare meaningfully intersect.

As always, this blog and podcast are for informational and educational purposes only and are not a substitute for personalized medical advice. Please talk to your own healthcare provider before starting or changing medications, hormones, or supplements.

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32: Mastering Your Sleep with Irina Macare
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32: Mastering Your Sleep with Irina Macare

Sleep isn’t just downtime — it’s an active, restorative process that directly impacts your hormonal balance, metabolism, mental health, and emotional resilience. For women in midlife, sleep can feel especially elusive. Hormonal fluctuations, stress, and lifestyle changes all intersect, often leading to insomnia, fatigue, and brain fog.

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia, a triple board-certified endocrinologist and women’s health expert, sits down with sleep coach Irina Macare to uncover the science and psychology behind sleep—and how we can all get it back.

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31: Empowering Women through Breast Health with Dr. Sasmita Misra
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31: Empowering Women through Breast Health with Dr. Sasmita Misra

Breast cancer remains the most common cancer among women worldwide, with one in eight women in the U.S. developing the disease in their lifetime. Early detection is one of the most powerful tools we have to improve survival rates and reduce the need for aggressive treatment.

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia speaks with Dr. Sasmita Misra, a fellowship-trained breast radiologist at the University of Chicago, to help women understand breast screening, risk factors, and new technologies that are changing the future of breast health.

This blog breaks down the science, clears up common misconceptions, and gives you a step-by-step guide to proactive breast cancer prevention.

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30: Becoming the Doctor My Mother Needed
Komal Patil-Sisodia Komal Patil-Sisodia

30: Becoming the Doctor My Mother Needed

This episode of Reset Recharge is different. In honor of Menopause Awareness Month, I wanted to slow down and share a story I’ve never fully told before — the story that shaped my purpose as a doctor, a daughter, and a woman.

It’s about my mom, her health journey, and the moment I realized that medicine could either make people feel invisible… or deeply seen. It’s also about how, decades later, her story became my own — and how that realization inspired me to build something new: a space where women can feel heard during one of the most transformative seasons of their lives — midlife and menopause.

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29: Metabolic Health & Breast Cancer: The Missing Link
Komal Patil-Sisodia Komal Patil-Sisodia

29: Metabolic Health & Breast Cancer: The Missing Link

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia explores how metabolic syndrome, insulin resistance, and dyslipidemia influence breast cancer risk — and how modern medications like statins, metformin, and GLP-1 receptor agonists fit into prevention and survivorship. Learn about metabolic health optimization, postmenopausal breast cancer risk, and evidence-based interventions for long-term wellness.

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28: Menopause, Hormones, & Diabetes Prevention
Komal Patil-Sisodia Komal Patil-Sisodia

28: Menopause, Hormones, & Diabetes Prevention

In this episode of Reset Recharge, Dr. Komal Patil-Sisodia explores a groundbreaking study that reveals how menopause hormone therapy (MHT) may actually reduce the risk of type 2 diabetes in perimenopausal women with prediabetes.

Dr. Komal unpacks the data from a major Diabetes and Metabolism study of over 6,500 women aged 46–60, showing that those who used hormone therapy were 30% less likely to develop diabetes. She explains the science behind how estrogen supports metabolic health — improving insulin sensitivity, lowering inflammation, reducing central fat gain, and supporting pancreatic function — and why timing, age, BMI, and ethnicity make all the difference.

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27: Becoming the CEO of Your Life with Dr. Una
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27: Becoming the CEO of Your Life with Dr. Una

If you’ve ever wondered how to honor your ambitions and your wellbeing, this episode is for you. Dr. Una—pediatrician, founder of EntreMD, and builder of multiple businesses—joined me to talk about motherhood, identity, and the practical systems that help women create time, joy, and wealth (in every sense of the word). Her story is a masterclass in learning new skills, delegating with intention, and aligning your roles so your life feels like one purpose instead of competing parts.

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26: Manifesting Your Best Life in Your 40s & Beyond with Sarah Centrella
Komal Patil-Sisodia Komal Patil-Sisodia

26: Manifesting Your Best Life in Your 40s & Beyond with Sarah Centrella

Have you ever noticed how easy it is to get caught in the same mental loops? Maybe you wake up already criticizing your body, worrying about your energy, or feeling anxious about the future. It can seem like no matter how hard you try, those thoughts keep circling back.

There’s a reason for that. Research suggests we think around 70,000 thoughts a day, and about 90 percent are the same ones we had yesterday. That means most of us are unintentionally reinforcing the very patterns we want to escape.

The good news is, it doesn’t have to stay that way. With a few simple practices, you can actually rewire your thought patterns and shift the way you experience your life. In this post, we’ll explore powerful mindset tools from Sarah Centrella, bestselling author, master life coach, and creator of the Centrella Method, including how to flip a negative thought in seconds, use affirmations to guide your growth, and create “future boards” that help bring your goals to life.

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25: Preventing Fractures: Osteoporosis Medications Explained
Komal Patil-Sisodia Komal Patil-Sisodia

25: Preventing Fractures: Osteoporosis Medications Explained

Osteoporosis medications often get a bad rap—but the science tells a very different story. Without treatment, bone loss can quietly progress until one fall or even a simple movement leads to a fracture. And those fractures aren’t just painful—they can mean months of recovery, ongoing pain, or even the loss of independence.

Now imagine the opposite: feeling strong enough to carry your groceries, climb the stairs with ease, or scoop up your grandkids without fear. That’s the real difference effective osteoporosis treatments can make.

In this post, we’ll explore the main medication options, who they’re right for, and what you need to know about side effects, safety, and timing—so you can make confident choices about protecting both your bones and your quality of life.

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24: Lifestyle Strategies for Bone Health
Komal Patil-Sisodia Komal Patil-Sisodia

24: Lifestyle Strategies for Bone Health

Which supplements really strengthen bones? Is walking enough to keep them strong or do you need something more? And how do you actually lower your risk of the kinds of falls that can change life overnight?

With advice coming from every direction, it's easy to waste time, money, and effort on things that don't truly make a difference. If you're over 50, post-menopausal, or simply planning to be stronger in the future, this second installment of my bone health series is packed with tools to help you take control of your bone health—starting today.

I'll share evidence-based strategies you can put into action right now, from spotting everyday habits that quietly weaken bones, to building an exercise routine proven to support bone density. We'll also cover simple, practical ways to make your home safer and reduce your risk of falls.

Read on for a clear, science-backed plan to protect your bones—and your independence—for years to come.

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23: Bone Health 101: What Every Woman Should Know
Komal Patil-Sisodia Komal Patil-Sisodia

23: Bone Health 101: What Every Woman Should Know

I see it all the time in my practice: women who feel perfectly fine put off their DEXA scans, brush off conversations about medication, or think, “That won’t happen to me.” But the reality is sobering. Half of all women over 50 will break a bone because of osteoporosis. And in many cases, it could have been prevented.

What makes osteoporosis so dangerous is how quietly it develops. There’s no pain, no obvious symptoms—just a seemingly harmless moment, like moving a coffee table or missing a step, that ends in a serious, sometimes life-altering fracture. By then, your independence and quality of life may already be at risk.

This blog kicks off a three-part series on bone health, designed to give you the knowledge and tools you need to protect yourself. We’ll break down how your bones function, how menopause affects them, and what you can do to stay strong, starting today. You'll also learn the difference between osteopenia and osteoporosis, and how to assess both your lifestyle and medical risk factors.

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22: Reclaiming Your Body in Midlife with Dr. Caissa Troutman
Komal Patil-Sisodia Komal Patil-Sisodia

22: Reclaiming Your Body in Midlife with Dr. Caissa Troutman

"I always felt like I was broken. I always felt that there was something wrong with me and I should have more willpower."

If this thought has ever crossed your mind as you've watched the scale creep up despite your best efforts, you're not alone. Dr. Caissa Troutman, quadruple board-certified physician and founder of Midlife reMDy, speaks these words from both professional expertise and personal experience—and her insights are revolutionizing how we understand midlife weight changes.

In a culture obsessed with the "calories in, calories out" model, women in perimenopause and menopause are told that weight gain is simply a matter of eating less and moving more. But what if everything we've been taught about midlife weight management is fundamentally flawed?

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21: The Perfect Storm: Parenting through Puberty & Perimenopause
Komal Patil-Sisodia Komal Patil-Sisodia

21: The Perfect Storm: Parenting through Puberty & Perimenopause

When you're navigating your own hormonal rollercoaster and parenting a teen on theirs, life can feel like one emotional aftershock after another. Puberty and perimenopause—two intense life transitions—can create the perfect storm at home. Emotions run high, communication stalls, and both mom and teen can end up feeling misunderstood or alone.

It’s not just the mood swings or the changing bodies. It’s the deeper identity shifts happening beneath the surface for both of you. And without the right support, this overlap can fuel resentment, emotional burnout, and a growing disconnect.

But it doesn’t have to.

In this post, we’ll explore insights from Kianna Carter, LICSW, a community mental health expert who works with adolescents and women across generations. From setting loving but firm boundaries to practicing self-compassion and building intentional check-ins, Kianna’s approach helps to strengthen family bonds, even in the midst of major change.

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20: When Hormones Change, Relationships Change with Neha Kumar LMFT
Komal Patil-Sisodia Komal Patil-Sisodia

20: When Hormones Change, Relationships Change with Neha Kumar LMFT

The statistics are striking: in the US, it's reported that up to 70% of divorces are initiated by women, with a notable spike occurring during the perimenopause years. Is this just coincidence, or is something deeper happening?

When hormonal shifts collide with long-term relationships, even the strongest partnerships can face unexpected challenges. These changes don't just affect the woman experiencing them—they ripple through her closest relationships, often creating confusion, conflict, and emotional distance that neither partner fully understands.

I recently spoke with my sister, Neha Kumar, a Licensed Marriage and Family Therapist with extensive experience helping couples navigate major life transitions, including perimenopause, to hear her insights on this often-overlooked relationship challenge.

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19: The Menopause-TMJD Connection with Dr. Priya Mistry
Komal Patil-Sisodia Komal Patil-Sisodia

19: The Menopause-TMJD Connection with Dr. Priya Mistry

As if menopause didn’t already come with enough challenges, many women are surprised to discover that the hormonal rollercoaster doesn’t just impact reproductive health—it can also wreak havoc on your jaw.

Fluctuating estrogen levels during menopause have been linked to TMJ (temporomandibular joint) disorders, which can cause jaw pain, clicking or popping sounds, difficulty chewing or speaking, and even headaches or facial pain. These symptoms are often overlooked or dismissed, yet they can seriously affect your daily life.

To better understand this connection, I spoke with my sister, Dr. Priya Mistry—a TMJ specialist who’s helped countless patients find relief from chronic pain. In our conversation, she explained the link between menopause and TMJ, how these symptoms often overlap with other conditions like sleep apnea, and what women can do to protect their jaw health during midlife.

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18: The Power of Your Internal Clocks: How Circadian Rhythms Shape Our Health with Lynne Peeples
Komal Patil-Sisodia Komal Patil-Sisodia

18: The Power of Your Internal Clocks: How Circadian Rhythms Shape Our Health with Lynne Peeples

For many women in midlife, sleep struggles, low energy, and weight changes can feel like an inevitable part of menopause. But an often overlooked culprit is circadian disruption. Hormonal shifts and the pace of modern life can throw off our internal clocks—the rhythms that regulate nearly every system in the body, from metabolism to mood.

When these clocks fall out of sync, it doesn’t just affect sleep. It can also disrupt hormone balance, increase the risk of chronic disease, and leave you feeling out of sorts without a clear reason why. And most of us have no idea how much these hidden clocks influence our daily lives—or how to get them back on track.

I recently spoke with science journalist Lynne Peeples, author of The Inner Clock: Living in Sync with Our Circadian Rhythms, who shared how menopause impacts circadian function and the powerful strategies she uses to restore rhythm and improve overall health—starting with small, daily shifts.

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